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267 GAS6, secreted by stromal cells such as CAFs and macrophages, binds to AXL, promoting its dimerization, autophosphorylation, and activation of downstream survival pathways, including the PI3K/AKT, MAPK/ERK, and NF-B pathways
Concurrently, NRF2 is engaged to mitigate oxidative stress and control cell cycle progression, enabling minimal residual disease and eventual relapse
Micronutrient deficiencies following bariatric surgery
Age is indeed just a number
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