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Non-peptidic oral GLP-1RAs may eventually reduce supply pressures because they do not require peptide synthesis or cold-chain storage, but this will depend on scalable, cost-efficient manufacturing pathways
In TriNetX, propensity score matching is performed using observed baseline covariates, such that patients without documented laboratory values (eg, hemoglobin A1c or body mass index) are excluded from the matched cohorts in favor of individuals with available data
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