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Results We included 1,647,238 patients who were prescribed a GLP-1 RA between January 2024 and July 2025, with 6,059,445 total GLP-1 RA prescriptions during this period

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Overstimulation of growth pathways may cause enlargement of bones in the hands, feet, or jaw, soft tissue thickening, and in severe cases, organomegaly (enlargement of organs)