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Laboratory studies of murine and non-human primates have demonstrated increased liver fat, hepatic inflammation, oxidative stress, and mitochondrial dysfunction in offspring of obese mothers fed a high-fat diet,(Reviewed in 9,33 ) The results of our metabolomic analysis of cord plasma add to the existing literature and suggest that lipotoxicity and increased oxidative stress also occur in infants born to mothers with obesity
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The link between melatonin and brain health has been clarified in more recent research by Chitimus et al., noting that melatonin has antioxidant properties and can help protect the brain from oxidative stress [14]
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