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How GHK-Cu Works (Mechanism of Action) GHK-Cu functions primarily as: A copper delivery molecule A modulator of gene expression A regulator of extracellular matrix remodelling Copper is an essential cofactor for enzymes involved in: Collagen cross-linking Angiogenesis Antioxidant defense Tissue remodelling GHK-Cu appears to: Increase synthesis of collagen types I and III Stimulate dermal fibroblast activity Modulate matrix metalloproteinases (MMPs) Reduce pro inflammatory signalling in wound models Its effects are local and tissue specific rather than systemic and hormonal
Beard JR, Officer A, Carvalho IA, Sadana R, Pot AM, Michel JP, Lloyd-Sherlock P, Epping-Jordan JE, Peeters GM, Mahanani WR, Thiyagarajan JA, Chatterij S (2016) The world report on ageing and health: a policy framework for healthy ageing
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Correct Relevant Nutrient Deficiencies Vitamin B6, B12, folate, riboflavin, choline, betaine, magnesium, zinc, selenium, glycine and cysteine availability may influence methylation, antioxidant protection and sulfur metabolism
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