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While GLP-1 receptor agonists are known to inhibit gallbladder motility, this case suggests that discontinuation may lead to a rebound hypercontractile state due to restored or hypersensitized CCK pathways
Antonoff M , Zeigler S On-The-Go Education: Mobile Software in Cardiothoracic Training
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This is exactly why we need Phase 3 trials and why calling something safe before long-term data exists is premature
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