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Confirmatory diagnostic studies should be performed prior to initiating therapy, if possible, and the patient should be followed with appropriate studies to demonstrate hematologic improvement (Hgb, hematocrit, RBC, reticulocyte count)
NICE advises taking diagnostic blood samples before starting vitamin B12 replacement where possible
However, the lasting effects of these injections can vary significantly between individuals, influenced by factors such as overall health, the severity of the deficiency, and the bodys absorption capacity
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