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Firstly, under conditions of insulin resistance, such as obesity and type 2 diabetes, GIP promotes lipid deposition in subcutaneous adipocytes [48]
For instance, administration must occur in a fasted state (at least 2-3 hours post-meal) because elevated insulin and blood glucose can significantly blunt the pituitarys response to secretagogues
When Nausea Is a Red Flag, Not a Phase Most nausea on Mounjaro is self-limited and dose-related
Certain patient factors may increase susceptibility to constipation on GLP-1 therapy
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