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Tirzepatide activates both GLP-1 and GIP receptors simultaneously, creating what researchers call a 'dual increttin receptor agonist' effect
Catherine Moore 2026-02-04Verified Purchase Excellent for studying NNMT's metabolic role
In the heart, validated studies find the receptor concentrated in the sinoatrial node, which explains the modest increase in heart rate, and in atrial myocytes, where it stimulates the release of atrial natriuretic peptide
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