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Scientists use these lab tests to guess how the compound might work in humans
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Preclinical data suggest that dual blockade of IL-4R and PD-1 leads to a more permissive immune landscape, characterized by reduced macrophage-mediated immune suppression and enhanced T cell infiltration
But the gut-lining and genotoxicity signals around sucralose, the IARC 2B label on aspartame, and the WHO's caution against relying on non-sugar sweeteners for health goals keep them at the bottom of my personal list
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