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[137] Laboratory [edit] The complete laboratory synthesis of B 12 was achieved by Robert Burns Woodward [138] and Albert Eschenmoser in 1972

Symptoms that may indicate low Vitamin B levels include fatigue, depression, low blood pressure, constipation, memory loss, weakness, sore tongue, tingling and numbness in fingers and toes, mood changes and difficulty walking

Methylcobalamin is a naturally occurring form that may offer added benefits for those with severe deficiencies or neurological symptoms