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Week-by-week dosage comparison Weight loss comparison at matched timepoints *Tirzepatide 24 and 48-week figures estimated from SURMOUNT-1 trajectory data, as primary endpoint was 72 weeks
The side effect profile of retatrutide, as observed in early clinical trials, shares many characteristics with other GLP-1-based therapies
Glucagon-driven thermogenesis
For the characterization of time-to-onset distribution patterns, we employed robust statistical descriptors, specifically the median value accompanied by the interquartile range (IQR), to account for potential distributional skewness and outlier effects
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