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Hippocampal GLP-1 receptors influence food intake, meal size, and effort-based responding for food through volume transmission
The mechanism of action centres on mimicking the naturally occurring hormone GLP-1, which is released from the intestine in response to food intake
It acts on a different receptor from GHRH analogues such as CJC-1295, which is why the two are frequently studied together
Read more in ADA Meeting News: Semaglutide trial results by Dr
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