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There are more than 10 functional (sub)isoforms of MTs, which are divided into four isoform classes, designated MT-1 to MT-4

Although cytotoxicity was not specific to homocysteine, endothelial cell detachment is also observed with cysteine (Dudman et al, 1991), an increase in the hydrogen peroxide-sensitive cellular fluorescent probe, 2,7-dichloro-fluorescein, was observed in cultured endothelial cells exposed to homocysteine (Toborek and Hennig, 1996)

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