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Lipogenesis Inhibition: In adipose tissue, NNMT inhibition reduces lipid accumulation by up to 70% (in vitro), shifting the cell's priority from fat storage to energy expenditure
It alters brain chemistry by inhibiting the reuptake of dopamine, norepinephrine, and serotonin the same neurotransmitters that regulate appetite, reward, mood, and energy
The study contributed to a developing preclinical literature suggesting AOD-9604 may have applications in joint and cartilage research distinct from its original metabolic indication
[114] Methyltransferases Methyl (CH 3 ) group transfers between two molecules
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