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However, in practice, it is usually difficult to perform several tests at different institutions because of time restrictions and the high volume of patients
This issue is particularly prominent in phase-II and phase-III clinical settings, where the inability to overcome physiological barriers is a critical hurdle [66]
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The molecular mechanisms that mediate the relationship between ELS, CAS and psychopathology revolve around interdependent signaling between mitochondrial metabolism, inflammatory immune responses and stress-responsive HPA signaling
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