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Nat Rev Endocrinol 19(3):164176 Perdomo CM, Cohen RV, Sumithran P et al (2023) Contemporary medical, device, and surgical therapies for obesity in adults
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Compounded semaglutide contains the same active ingredient and works through the same mechanism when sourced from a licensed 503B compounding pharmacy
There are more nerves in the muscle in the thigh than in the deltoid muscle, and it is easier to find the safe place to do the injection in the upper arm (which is why this is a common used place to give vaccinations i.m.)
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