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8226/S, 8226/S-CR, 8226/S-ATOR05 cells were treated with 2 M ATO for 0, 6, or 24 h, protein expression was determined by Western blot and membranes were probed with antibodies against proteins involved in the (A) antioxidant response or (B) the Bcl-2 family
GHK-Cu (Copper Peptide GHK-Cu) is a naturally occurring tripeptide (glycine-histidine-lysine) complexed with copper(II) ions
Accumulated cellular iron generates cytotoxic hydroxyl radicals (OH) via the Fenton reaction
Activating them improves insulin sensitivity and may enhance fat metabolism through pathways that GLP-1 alone does not reach
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