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In neurons, Grx has a protective effect on redox-sensitive enzymes and ion channels, meaning that its dysfunction is implicated in several neurodegenerative disorders involving protein misfolding and redox signaling dysregulation (Ogata et al., 2021)
It commonly develops alongside spasticity, muscle weakness, and hyperreflexia
It belongs to the GLP-1 class but represents the third generation of that class
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