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A very large fraction of published binding constants for melanocortin ligands, including those for cyclic analogues, peptidomimetics and candidate subtype-selective compounds, are reported as inhibition of I-NDP-alpha-MSH binding to membranes from cell lines stably expressing a single human receptor subtype

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As a "triple G" agonist, it targets GLP-1, GIP, and glucagon (GCG) receptors, which play a crucial role in regulating blood sugar levels, appetite, and hunger