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CagriSema, under investigation for people with obesity as well as type 2 diabetes, has also shown weight loss (up to 15.6% reduction) as well as improved A1C (up to 2.18% reduction) in its phase 2 clinical trial

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The most common side effects are injection-site soreness (41%, lasting 24-36 hours), mild nausea (12-15%, lasting 4-8 hours), and skin flushing (8-10%, lasting 10-30 minutes)