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In fact, as of this writing, there is only one small retrospective study involving intra-articular knee injection into patients experiencing non specific knee pain
This effect has been documented in corneal studies (Sosne 2011) and in muscular dystrophy models (Spurney 2010, PMC2813286 DMD models)
A 2024 study using specialized delivery systems found that copper peptide formulations increased activation of key proteins in this pathway
The method of giving the shot, like intramuscular, subcutaneous, or intravenous, affects the dose
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