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To date, semaglutide and tirzepatide have not been systematically studied for their safety and efficacy in people with PWS
Semaglutide is typically administered via a once-weekly injection
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Because tirzepatide engages two receptor systems, clinical studies show approximately 20-22% body weight reduction at highest doses versus 15-17% for semaglutide, making it the more potent option for patients whove plateaued or need faster results
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