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[Glutathione-S-transferase and glutathione in the liver and blood of rats poisoned by [PMID: 7448078] Laboratory literature summary: [Glutathione-S-transferase and glutathione in the liver and blood of rats poisoned by thioacetamide]

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Studies have shown that lactate can inhibit the polarization of M1 proinflammatory macrophages while promoting the polarization of M2 macrophages toward an anti-inflammatory and proangiogenic phenotype, with these effects being mediated through various mechanisms, including histone posttranslational modifications and signaling pathway regulation (107, 108)