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14 While tirzepatide has shown positive effects on markers of cardiovascular health like blood pressure and lipids, its dedicated cardiovascular outcomes trial (SURPASS-CVOT) is still ongoing
Common experience points include: Early weeks may bring reduced appetite and earlier fullness Some people notice less interest in heavy or greasy foods Weight loss often becomes clearer after dose increases and consistent routines Hydration and protein help reduce fatigue and support lean mass Strength training supports metabolism and improves body composition Weekly injections are usually simple and quick
This reduction contributes to fatigue, sluggish metabolism, and decreased cognitive performance
Aug 2010;12(4):365-80
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