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Where appetite circuitry is examined, immediate-early gene markers and neuropeptide expression in hypothalamic nuclei can complement behavioral readouts
To test this, we stained cells with fluorescent dyes labelling cytoplasm or plasma membrane and quantified the flat, protrusive peripheral parts of the cell using a custom-made image analysis pipeline (Methods
And unlike semaglutide, the weight loss trajectory with retatrutide did not appear to plateau at 48 weeks
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