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Metformin suppressed oxidative stress through promoting Nrf2, NQO1, and HO-1 expression in MIA-induced mouse model Oxidative stress is a major causative factor in OA development 30

This pathway contributes to both the development and exacerbation of asthma by mediating the release of pro-inflammatory cytokines such as IL1 and IL18, which are critical in the pathogenesis of severe steroid-resistant asthma (SSRA) and other asthma phenotypes [148, 149]

The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis

This method allows for better absorption of vitamins compared to oral supplements, ensuring that the body receives the maximum benefit