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In the treatment-policy estimand analysis, at week 26 oral semaglutide (1.2% mean A1C reduction from baseline) met criteria for noninferiority when compared with liraglutide (1.1% mean A1C reduction from baseline) and met criteria for superiority when compared with placebo (0.2% mean A1C reduction from baseline
Tesofensine, a triple monoamine reuptake inhibitor (SNDRI), is also being studied for its dual impact on stimulant use and obesity
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