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4 Regulatory mechanisms of L-carnitine on hepatocyte function Clinical evidence indicates that L-carnitine improves liver function in NAFLD patients, reflected by reduced serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels (37, 63)

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Pinto C, Hao R, Grimaldi M, Thrikawala S, Boulahtouf A, Ait-Aissa S, et al

The increased PEP also inhibited phosphofructose kinase (encoding by pfk ) activity, which was responsible for the decreased glycolytic flux and the down regulation of the glycolytic activities [33]