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For instance, Bunck et al
Padawer J
The lack of efficacy of inhaled GSH in patients with cystic fibrosis could be explained by the high concentrations of the GSH-degrading enzyme -glutamyltransferase present in lung fluids of those patients (116123), and then, the use of precursors of GSH synthesis like NAC and cystine could be more effective in the synthesis of GSH (124)
Afemelanotide is now approved by the United States Food and Drug Administration (FDA) to treat the skin disorder erythropoietic protoporphyria [7]
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