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The PZQ plasma exposure, measured by C max , is substantially lower than the LD 50 against adult worms and NTS reported by others 61,62 , and substantially below the LD 50 for NTS killing measured herein (2743 M)

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While Turner et al.s primary results suggested that resveratrol has potential in slowing functional decline, other clinical assessments, including the Clinical Dementia Rating-Sum of Boxes, ADAS-cog, MMSE, and Neuropsychiatric Inventory do not reflect this effect [77]