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The thing is that all of these showed promise but ultimately proved very little
Characterization of the human Omega class glutathione transferase genes and associated polymorphisms
Mastromarino P, Hemalatha R, Barbonetti A, et al
N-Acetyl-p-benzoquinone imine (NAPQI), the toxic metabolite of APAP, besides its intrinsic ability to form aspecific chemical adducts with proteins, promotes the excessive accumulation of ROS mostly depleting the GSH pool that it is required for its detoxification
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