for example, isoniazid, cycloserine, penicillamine, and hydralazine each form complexes with B or otherwise interfere with B metabolism, potentially leading to deficiency and peripheral neuropathy
In addition, other tissue metabolism disorders also occur, such as nervous system damage
Furthermore, there were no significant negative impacts on liver function, renal function, hematology, or vital signsduring or after the supplementation period Supplementary Tables 24
Preclinical studies in rodent models have examined its interactions with nitric oxide signaling, angiogenic factors including VEGF, fibroblast migration, and collagen synthesis in various tissue types