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To the point where, as an obesity medicine specialist, I rarely prescribe metformin as an anti-obesity medication unless there are compelling reasons against using other anti-obesity medications. He does, however, prescribe it to prevent weight gain from certain conditions or medications for which putting on pounds is a common side effect

Relationships between obesity and DSM-IV major depressive disorder, suicide ideation, and suicide attempts: results from a general population study

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One less common but disturbing potential side effect of the drug, which is sold under the brand names Ozempic and Wegovy: Hair loss