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It inhibited caspase-3 in brain tissue and OGD/R-treated neurons (Zhang et al., 2017
Additionally, a surgical study found no increased risk of pulmonary complications in GLP1-RA-treated patients with T2D (n = 3,502) compared to patients with T2D who were treated with other antihyperglycaemic medications (n = 23,679) [19], further questioning the need for prolonged perioperative GLP1-RA pausation [10]
By integrating neurobiological and epigenetic perspectives, this review offers a clearer framework for understanding addiction and depression comorbidity and points to promising therapeutic opportunities
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