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A 2018 study showed that NAC may be helpful in the treatment of those with bipolar depression while a 2016 study suggests that NAC may be helpful when taken in addition to routine medications used to treat schizophrenia
10.1152/physrev.00034.2006 Physiol
Pralidoxime remains the only oxime FDA-approved for use in organophosphate poisoning in the US
Clinical trials use standardized tools to capture side effects, and fatigue may not consistently meet formal reporting thresholds in those frameworks
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