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As we age, our NAD+ levels naturally drop

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For example, GRACILE syndrome ( G rowth R etardation, A mino aciduria, C holestasis, I ron overload, L actic acidosis, and E arly death) is caused by mutations in the BCS1L gene which is required for proper assembly of complex III

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My project aims to dissect the regulation of inflammatory response against fungal and bacterial keratitis with the goal of a more targeted treatment for the disease

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GSH is synthesized via two ATP-dependent enzymatic steps catalyzed by glutamate-cysteine ligase (GCL) and glutathione synthetase

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