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These efforts should be directed toward maintaining good nutritional intake during this period, rapidly instituting therapy for superimposed illnesses, and maintaining good nutritional support during such illnesses
It should not be used in patients with type 1 diabetes or in patients with diabetic ketoacidosis
Semaglutide is widely used in people with type 2 diabetes
This would be in line with preclinical observations that incretin receptor expression is down-regulated by exposure to high glucose, and improves once normoglycaemia is restored (48), and that dys-regulation of glycaemic control in otherwise healthy humans leads to impaired incretin actions (49)
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