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It is usually recommended to have a treatment every four weeks to eliminate the buildup of dead skin cells

Presented for research literature review only Watabe T et al

539 Results from several Phase III clinical trials (ORION-9/10/11, NCT03397121, NCT03399370, and NCT03400800) have shown that subcutaneous injections of inclisiran every 6 months considerably reduce LDL-C levels by 4852%, demonstrating sustained efficacy and good tolerability

One troubling side effect of the use of DPP4 inhibitors is severe joint pain, so much so that the US FDA issued a Drug Safety Communication warning of this problem

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