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In vivo studies demonstrated that the G/D-CuP accelerated the three phases of diabetic wound repair (inflammation, proliferation, and remodeling)
Systemic oxidative stress and visceral adipose tissue mediators of NLRP3 inflammasome and autophagy are reduced in obese type 2 diabetic patients treated with metformin
However, glutathione levels can decrease due to such factors as aging, stress, pollution, smoking, poor nutrition, and lack of sleep
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