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Esposito K, Maiorino MI, Bellastella G, Chiodini P, Panagiotakos D, Giugliano D

The large dark patches of pigmentation caused by overactive melanocytes may appear as mask-like patches on the cheeks, temples, above the upper lip and/or forehead

Carnitine transporter mutations in Crohn's disease consists of missense mutation(s) in the gene coding plasma membrane transporter OCTN1 (SLC22A4) and/or mutation(s) in the promoter of the gene encoding OCTN2 (SLC22A5) [14, 35]