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2.3 Experimental protocol Following 1 week of acclimation, six rats were allocated randomly to one of four groups: Rats in Group 1, the control group, were given saline intraperitoneally (IP) twice weekly for 6 weeks

2.6 Cognitive dysfunction Cognitive dysfunction in LC patients is characterized by a range of symptoms, including memory decline, attention deficits, executive dysfunction, and reduced language fluency, often accompanied by psychological distress (41)