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If youre falling asleep at dangerous moments or unable to function, you may need a slower titration, a dose adjustment, or a check for vitamin deficiencies like B12, iron, or vitamin D

The oxidation of key stem cell proteins (-catenin) by radiation-induced reactive oxygen species (ROS) destabilizes Wnt signaling, hinders the self-renewal function of stem cells and eventually destroys intestinal epithelial cells and induces apoptosis of crypt stem cells 31

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