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The reduced stomach capacity and slower gastric emptying from GLP-1 activation make large meals uncomfortable
Even with a letter of medical necessity, most administrators will still deny reimbursement
The pen designs are intended for patient self-administration, with upper arm injections generally recommended to be administered by a caregiver
This was further supported by a 2018 randomized, double-blind study by Hewlings et al., which evaluated healthy participants exposed to a standardized allergen challenge
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