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In an animal model, semaglutide demonstrated neuroprotective effects and improved cognitive function by inhibiting the release of inflammatory cytokines mediated by the NLRP3 inflammasome, a protein involved in regulating the innate immune system and inflammatory responses

Boku S, Satake H, Mitani S, Maeda K, Kudo T, Yamaguchi T, et al

Semaglutide GLP-1 is a GLP-1 agonist, known as a Glucagon-Like Peptide-1, which works on receptors in the brain as well as the pancreas to cause a decrease in appetite along with slowing of the digestion process which leads to feeling full longer

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