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Vukojevi J, Siroglavi M, Kanik K, Kralj T, Stani D, Kokot A, et al
For people with MTHFR mutations, synthetic folic acid can actually block folate receptors and worsen symptoms
Calcium upregulation by percutaneous administration of gene therapy in patients with cardiac disease (CUPID 2): a randomised, multinational, double-blind, placebo-controlled, phase 2b trial
Following this spike, switching rates declined but remained elevated through September 2025 at 1.6% on average before returning to an average baseline level of 0.6% between October 2025 and February 2026
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