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To investigate the functional role of these residues, we generated phosphorylation-deficient mutants by site-directed mutagenesis, substituting threonine (T) with alanine (A) (designated as T73A and T397A, respectively)
Yes, gradually over several weeks to months, maintaining results requires ongoing use or periodic cycles
A general rule of thumb: Half your body weight (in pounds) = ounces of water per day
"Any time you add a receptor target, you add a dimension of unpredictability in pediatric populations," noted Dr
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