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A drug-drug interaction trial of oral semaglutide with levothyroxine and multiple coadministered tablets
Studies from the US Food and Drug Administration (FDA) have found a disproportionate reporting of suicidal ideation and depression/suicidal thoughts with semaglutide and liraglutide, but not for suicidal behaviour, suicide attempts and completed suicide [27,28,29,30]
Since everyones weight loss journey is different, the timeline for results may vary
Our negative control outcome analyses (car accidents) showed no association between GLP-1RA initiation and new-onset AF/Aflutter, which is reassuring, though unmeasured confounders like variation on weight reduction and TSH may remain
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