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According to the SAR study, replacing ENDO3 pyridine ring with a heterocyclic scaffold, 1 H -imidazo[4,5-b] pyrazine (ENDO14) or rearrangement of the bromine and methyl substituents on the pyridine ring (ENDO17, ENDO18 and ENDO19) did not improve activity
J Endocrinol Invest 44(9):18271835
None of it did much good unless the patient didnt have enough B12 based on a blood test
Carnitine became especially popular after rumors circulated that it helped the Italian national soccer team to become world champions in 1982
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