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Speak with your healthcare provider before stopping or changing your medication

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Direct Receptor-Mediated Effects : While preclinical studies suggest GLP-1 receptors may be present in bone tissue, the clinical relevance of direct receptor activation in human bone cells remains uncertain and controversial

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Phosphorylated Smad2 associates with STAT3 to facilitate Th17 cell polarization, whereas unphosphorylated Smad3 interacts with STAT3 to inhibit Th17 cell differentiation

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